{"id":2005,"date":"2017-07-31T19:36:44","date_gmt":"2017-07-31T19:36:44","guid":{"rendered":"http:\/\/cytologystuff1.wpengine.com\/non-gyn-atlas\/effusions-and-washes-ovarian-adenocarcinoma\/"},"modified":"2025-02-10T20:03:11","modified_gmt":"2025-02-10T20:03:11","slug":"effusions-and-washes-ovarian-adenocarcinoma","status":"publish","type":"page","link":"https:\/\/dev.cytologystuff.com\/zh-hans\/non-gyn-atlas\/effusions-and-washes-ovarian-adenocarcinoma\/","title":{"rendered":"Effusions and Washes – Ovarian Adenocarcinoma"},"content":{"rendered":"

[vc_row 0=””][vc_column 0=”” offset=”vc_hidden-lg vc_hidden-md”][vc_raw_html 0=””]JTNDY2VudGVyJTNFJTNDYSUyMGNsYXNzJTNEJTIyc2hpZnRuYXYtdG9nZ2xlJTIwc2hpZnRuYXYtdG9nZ2xlLWJ1dHRvbiUyMiUyMGRhdGEtc2hpZnRuYXYtdGFyZ2V0JTNEJTIyc2hpZnRuYXYtbWFpbiUyMiUzRSUzQ2klMjBjbGFzcyUzRCUyMmZhJTIwZmEtYmFycyUyMiUzRSUzQyUyRmklM0UlMjBUYWJsZSUyMG9mJTIwQ29udGVudHMlMjAlM0MlMkZhJTNFJTNDJTJGY2VudGVyJTNF[\/vc_raw_html][\/vc_column][\/vc_row][vc_row][vc_column][vc_custom_heading text=”Cytology of Pleural, Pericardial and Peritoneal Cavity Effusions – Effusions and Washes Ovarian Adenocarcinoma” font_container=”tag:h1|text_align:center” use_theme_fonts=”yes”][\/vc_column][\/vc_row][vc_row el_id=”acknowledgements”][vc_column width=”2\/3″][vc_column_text]<\/a><\/p>\n

EFFUSIONS AND WASHES – OVARIAN ADENOCARCINOMA<\/p>\n

An unexplained peritoneal effusion in a female patient should prompt an assessment for malignant cells of ovarian origin<\/p>\n

<\/a><\/p>\n

\n

Reminder: You may click on any slide image
\nfor an enlarged view.<\/strong><\/p>\n


\n\"Image<\/a><\/p>\n
\n

Figure 43<\/strong>
\nPleural effusion: Papillary serous ovarian adenocarcinoma. 20X<\/p>\n<\/div>\n<\/div>\n

Figure 43<\/strong>
\nPleural effusion:
\nPapillary serous ovarian adenocarcinoma.
\n20X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 44<\/strong>
\nPleural effusion: Papillary serous ovarian adenocarcinoma. 40X<\/div>\n<\/div>\n
Figure 44<\/strong>
\nPleural effusion:
\nPapillary serous ovarian adenocarcinoma.
\n40X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 45<\/strong>
\nPleural effusion: Papillary serous ovarian adenocarcinoma. 60X<\/div>\n<\/div>\n
Figure 45<\/strong>
\nPleural effusion:
\nPapillary serous ovarian adenocarcinoma.
\n60X<\/div>\n
<\/div>\n

Figures 43-45:<\/strong> Pleural effusion Papillary serous ovarian adenocarcinoma.
\nCells of papillary serous ovarian adenocarcinoma in a pleural effusion represent a discontinuous population of cells. Their cell and nuclear size is variable. Increased nuclear to cytoplasmic ratio and cytoplasmic vacuoles are features. Cells may exist singly or in small acinar groups.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 46<\/strong>
\nPleural effusion: Serous ovarian adenocarcinoma. These tumor cells, metastatic from an ovarian adenocarcinoma and found in a pleural effusion, were shed as a three-dimensional papillary \u2013 glandular structure. 40X<\/div>\n<\/div>\n
Figure 46<\/strong>
\nPleural effusion:
\nSerous ovarian adenocarcinoma. These tumor cells, metastatic from an ovarian adenocarcinoma and found in a pleural effusion, were shed as a three-dimensional papillary \u2013 glandular structure.
\n40X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 47<\/strong>
\nPleural effusion: Serous ovarian adenocarcinoma. Though three-dimensional, the malignant nature of these ovarian cancer cells is easily appreciated when comparing their size to lymphocytes in the background. Distinction between ovarian and endometrial sources may be difficult given the common Mullerian origin of tumors in each site. 20X<\/div>\n<\/div>\n
Figure 47<\/strong>
\nPleural effusion:
\nSerous ovarian adenocarcinoma. Though three-dimensional, the malignant nature of these ovarian cancer cells is easily appreciated when comparing their size to lymphocytes in the background. Distinction between ovarian and endometrial sources may be difficult given the common Mullerian origin of tumors in each site.
\n20X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 48<\/strong>
\nPleural effusion: Serous ovarian adenocarcinoma. Sheets of tumor cells with large nuclei and prominent nucleoli. Again note the size difference in comparison to background lymphocytes. This is a discontinuous cell population. 40X<\/div>\n<\/div>\n
Figure 48<\/strong>
\nPleural effusion:
\nSerous ovarian adenocarcinoma. Sheets of tumor cells with large nuclei and prominent nucleoli. Again note the size difference in comparison to background lymphocytes. This is a discontinuous cell population.
\n40X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 49<\/strong>
\nPeritoneal effusion: Serous borderline tumor. Papillary cluster of glandular serous borderline tumor forming rounded “cannon-balls” of tumor cells. Note the smooth border, compared to the scalloped border of reactive mesothelial cells 60X<\/div>\n<\/div>\n
Figure 49<\/strong>
\nPeritoneal effusion:
\nSerous borderline tumor. Papillary cluster of glandular serous borderline tumor forming rounded “cannon-balls” of tumor cells. Note the smooth border, compared to the scalloped border of reactive mesothelial cells
\n60X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 50<\/strong>
\nPeritoneal wash: Ovarian serous borderline tumor. Papillary cluster of tumor cells with prominent cytoplasmic vacuolization. 40X<\/div>\n<\/div>\n
Figure 50<\/strong>
\nPeritoneal wash:
\nOvarian serous borderline tumor. Papillary cluster of tumor cells with prominent cytoplasmic vacuolization.
\n40X<\/div>\n
<\/div>\n

Vigorous peritoneal washes may dislodge microscopic tumor. Washes are an integral part of staging laparoscopy. Because of the washing procedure, tumor cells generally come off in three- dimensional cohesive groups and may be admixed with sheets of benign mesothelium. The tumor cells are easily distinguished by size, malignant characteristics and crowded configurations.<\/p>\n


\n\"Image<\/a><\/p>\n
Figure 51<\/strong>
\nPelvic wash: Ovarian serous borderline tumor. This pelvic wash has produced a three-dimensional crowded cluster of tumor cells with minimal atypical nuclear features. 40X<\/div>\n<\/div>\n
Figure 51<\/strong>
\nPelvic wash:
\nOvarian serous borderline tumor. This pelvic wash has produced a three-dimensional crowded cluster of tumor cells with minimal atypical nuclear features.
\n40X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 52<\/strong>
\nPeritoneal effusion: Serous ovarian adenocarcinoma. Pleomorphic, papillary groups of tumor cells, found in a peritoneal effusion. Note the size difference between tumor cells and the benign mesothelial cells at lower right. 40X<\/div>\n<\/div>\n
Figure 52<\/strong>
\nPeritoneal effusion:
\nSerous ovarian adenocarcinoma. Pleomorphic, papillary groups of tumor cells, found in a peritoneal effusion. Note the size difference between tumor cells and the benign mesothelial cells at lower right.
\n40X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 53<\/strong>
\nPeritoneal effusion: Ovarian adenocarcinoma. A three-dimensional tumor cell group is seen along with a “dirty” background. 20X<\/div>\n<\/div>\n
Figure 53<\/strong>
\nPeritoneal effusion:
\nOvarian adenocarcinoma. A three-dimensional tumor cell group is seen along with a “dirty” background.
\n20X<\/div>\n
<\/div>\n

\n\"Image<\/a><\/p>\n
Figure 54<\/strong>
\nPelvic wash: Ovarian adenocarcinoma. A malignant three-dimensional cell group contrasts with a group of four benign cells at upper left. 40X<\/div>\n<\/div>\n
Figure 54<\/strong>
\nPelvic wash:
\nOvarian adenocarcinoma. A malignant three-dimensional cell group contrasts with a group of four benign cells at upper left.
\n40X<\/div>\n<\/div>\n
<\/div>\n

[\/vc_column_text][vc_column_text css=”.vc_custom_1500390293825{margin-top: 30px !important;}” el_class=”back-to-top”]Back to Top<\/a><\/strong>[\/vc_column_text][\/vc_column][vc_column width=”1\/3″ offset=”vc_hidden-sm vc_hidden-xs”][vc_widget_sidebar sidebar_id=”consulting-right-sidebar”][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"

[vc_row 0=””][vc_column 0=”” of<\/p>\n","protected":false},"author":7,"featured_media":0,"parent":1947,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-2005","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/dev.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages\/2005","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dev.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/dev.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/dev.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/dev.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/comments?post=2005"}],"version-history":[{"count":0,"href":"https:\/\/dev.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages\/2005\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/dev.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/pages\/1947"}],"wp:attachment":[{"href":"https:\/\/dev.cytologystuff.com\/zh-hans\/wp-json\/wp\/v2\/media?parent=2005"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}